1,25(OH)(2)D(3) downregulates the Toll-like receptor 4-mediated inflammatory pathway and ameliorates liver injury in diabetic rats

BACKGROUND: Fatty acid deposition in the liver can activate a number of pro-inflammatory signaling pathways such as the Toll-like receptor 4 (TLR4) pathway, which may be important in the pathogenesis of nonalcoholic steatohepatitis. 1,25(OH)(2)D(3) downregulates the expression of TLR4 and may repres...

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Detalles Bibliográficos
Autores principales: Wang, H., Zhang, Q., Chai, Y., Liu, Y., Li, F., Wang, B., Zhu, C., Cui, J., Qu, H., Zhu, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768236/
https://www.ncbi.nlm.nih.gov/pubmed/25906757
http://dx.doi.org/10.1007/s40618-015-0287-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768236/
https://www.ncbi.nlm.nih.gov/pubmed/25906757
http://dx.doi.org/10.1007/s40618-015-0287-6

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