Cargando…

1,25(OH)(2)D(3) downregulates the Toll-like receptor 4-mediated inflammatory pathway and ameliorates liver injury in diabetic rats

BACKGROUND: Fatty acid deposition in the liver can activate a number of pro-inflammatory signaling pathways such as the Toll-like receptor 4 (TLR4) pathway, which may be important in the pathogenesis of nonalcoholic steatohepatitis. 1,25(OH)(2)D(3) downregulates the expression of TLR4 and may repres...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, H., Zhang, Q., Chai, Y., Liu, Y., Li, F., Wang, B., Zhu, C., Cui, J., Qu, H., Zhu, M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768236/ https://www.ncbi.nlm.nih.gov/pubmed/25906757 http://dx.doi.org/10.1007/s40618-015-0287-6

Ejemplares similares

Association among plasma 1,25(OH)(2)D, ratio of 1,25(OH)(2)D to 25(OH)D, and prostate cancer aggressiveness
por: Ramakrishnan, Swathi, et al.
Publicado: (2019)

1,25(OH)(2)D(3) inhibits osteogenic differentiation through activating β-catenin signaling via downregulating bone morphogenetic protein 2
por: Han, Xiaofeng, et al.
Publicado: (2020)

Antidepressants differentially related to 1,25-(OH)(2) vitamin D(3) and 25-(OH) vitamin D(3) in late-life depression
por: Oude Voshaar, R C, et al.
Publicado: (2014)

1,25(OH)(2)D(3) ameliorates doxorubicin‑induced cardiomyopathy by inhibiting the NLRP3 inflammasome and oxidative stress
por: Gu, Xin, et al.
Publicado: (2023)

Multiple Sclerosis Patients Show Lower Bioavailable 25(OH)D and 1,25(OH)(2)D, but No Difference in Ratio of 25(OH)D/24,25(OH)(2)D and FGF23 Concentrations
por: Vlot, Mariska C, et al.
Publicado: (2019)

Vitamin D and 1,25(OH)(2)D Regulation of T cells
por: Cantorna, Margherita T., et al.
Publicado: (2015)

25(OH)D-but not 1,25(OH)(2)D–Is an independent risk factor predicting graft loss in stable kidney transplant recipients
por: Zeng, Shufei, et al.
Publicado: (2023)

25(OH)D and 1,25(OH)D vitamin D fails to predict sepsis and mortality in a prospective cohort study
por: Ratzinger, Franz, et al.
Publicado: (2017)

1,25-(OH)(2)D(3) ameliorates renal interstitial fibrosis in UUO rats through the AMPKα/mTOR pathway
por: Tian, Shasha, et al.
Publicado: (2021)

Does Sevelamer Hydrochloride (Renagel) Influence 25(Oh)D3 and 1,25(Oh)2D3 Level in Haemodialysis Patients?
por: Strózecki, Pawel, et al.
Publicado: (2005)

25(OH)D(3) and 1.25(OH)(2)D(3) inhibits TNF-α expression in human monocyte derived macrophages
por: Rafique, Aisha, et al.
Publicado: (2019)

MON-LB74 The Problem of Measuring 1,25(OH)2 Vitamin D in Patients With High Levels of 25(OH) Vitamin D
por: Vieira, Jose Gilberto, et al.
Publicado: (2020)

Circulatory 25(OH)D and 1,25(OH)(2)D as differential biomarkers between multiple system atrophy and Parkinson's disease patients
por: Ogura, Hiromu, et al.
Publicado: (2021)

1,25-Dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) Signaling Capacity and the Epithelial-Mesenchymal Transition in Non-Small Cell Lung Cancer (NSCLC): Implications for Use of 1,25(OH)(2)D(3) in NSCLC Treatment
por: Upadhyay, Santosh Kumar, et al.
Publicado: (2013)

1,25-hydroxyvitamin D relieves colitis in rats via down-regulation of toll-like receptor 9 expression
por: Dai, Zhang-han, et al.
Publicado: (2015)

The metabolism of 1,25(OH)(2)D(3) in clinical and experimental kidney disease
por: Turner, Mandy E., et al.
Publicado: (2022)

1,25-(OH)(2)D(3)/Vitamin D receptor alleviates systemic lupus erythematosus by downregulating Skp2 and upregulating p27
por: Liu, Dan, et al.
Publicado: (2019)

1,25(OH)(2)D(3) Promotes the Efficacy of CD28 Costimulation Blockade by Abatacept
por: Gardner, David H., et al.
Publicado: (2015)

Effects of 1,25(OH)(2)D(3) and 25(OH)D(3) on C2C12 Myoblast Proliferation, Differentiation, and Myotube Hypertrophy
por: van der Meijden, K., et al.
Publicado: (2016)

Metabolic Advantage of 25(OH)D(3) versus 1,25(OH)(2)D(3) Supplementation in Infantile Nephropathic Cystinosis-Associated Adipose Tissue Browning and Muscle Wasting
por: Zhou, Ping, et al.
Publicado: (2022)

1,25(OH)(2)D(3) Deficiency Induces Colon Inflammation via Secretion of Senescence-Associated Inflammatory Cytokines
por: Liu, Yun, et al.
Publicado: (2016)

Anti-Inflammatory Effects of 1,25(OH)2D/Calcitriol in T Cell Immunity: Does Sex Make a Difference?
por: Peruzzu, Daniela, et al.
Publicado: (2022)

Vitamin D (1,25(OH)(2)D3) induces α-1-antitrypsin synthesis by CD4(+) T cells, which is required for 1,25(OH)(2)D3-driven IL-10
por: Dimeloe, Sarah, et al.
Publicado: (2019)

Treatment with 1,25(OH)(2)D(3)induced HDAC2 expression and reduced NF-κB p65 expression in a rat model of OVA-induced asthma
por: Zhou, Y., et al.
Publicado: (2015)

Recruitment, augmentation and apoptosis of rat osteoclasts in 1,25-(OH)(2)D(3) response to short-term treatment with 1,25-dihydroxyvitamin D(3)in vivo
por: Miao, Dengshun, et al.
Publicado: (2002)

Downregulation of miR-302c and miR-520c by 1,25(OH)2D3 treatment enhances the susceptibility of tumour cells to natural killer cell-mediated cytotoxicity
por: Min, D, et al.
Publicado: (2013)

1,25(OH)(2)D(3) Protects Liver Fibrosis Through Decreasing the Generation of TH17 Cells
por: Gu, Lei, et al.
Publicado: (2017)

Vitamin D and the Ability to Produce 1,25(OH)(2)D Are Critical for Protection from Viral Infection of the Lungs
por: Arora, Juhi, et al.
Publicado: (2022)

1,25(OH)(2)D(3) dependent overt hyperactivity phenotype in klotho-hypomorphic mice
por: Leibrock, Christina B., et al.
Publicado: (2016)

Without 1α-hydroxylation, the gene expression profile of 25(OH)D(3) treatment overlaps deeply with that of 1,25(OH)(2)D(3) in prostate cancer cells
por: Susa, Takao, et al.
Publicado: (2018)

The 25(OH)D3, but Not 1,25(OH)2D3 Levels Are Elevated in IBD Patients Regardless of Vitamin D Supplementation and Do Not Associate with Pain Severity or Frequency
por: Zielińska, Anna, et al.
Publicado: (2021)

Proposal of a bioinformatics approach to predict molecular mechanisms involved in inflammatory response: case of ATRA and 1,25(OH)(2)D in adipocytes
por: Karkeni, Esma, et al.
Publicado: (2023)

Angiotensin 1–7 ameliorates caerulein-induced inflammation in pancreatic acinar cells by downregulating Toll-like receptor 4/nuclear factor-κB expression
por: Wang, Yan, et al.
Publicado: (2018)

Additive Effects of VDBP and 1,25(OH)2D3 on the Viability and Apoptosis of Rheumatoid Arthritis Synovial Fibroblasts
por: Zhang, Yeyong, et al.
Publicado: (2021)

The Impact of Estradiol and 1,25(OH)2D3 on Metabolic Syndrome in Middle-Aged Taiwanese Males
por: Cheng, Kai-Hung, et al.
Publicado: (2013)

1,25 (OH)(2)D(3) treatment alters the granulomatous response in M. tuberculosis infected mice
por: Bhatt, Kamlesh, et al.
Publicado: (2016)

Promoting effect of 1,25(OH)(2) vitamin D(3) in osteogenic differentiation from induced pluripotent stem cells to osteocyte-like cells
por: Kato, Hiroshi, et al.
Publicado: (2015)

In Vitro Differentiation of Preosteoblast-Like Cells, MC3T3-E1, to Adipocytes Is Enhanced by 1,25(OH)(2) Vitamin D(3)
por: Pendleton, Elisha, et al.
Publicado: (2017)

1,25(OH)2D3 Attenuates IL-1β-Induced Epithelial-to-Mesenchymal Transition Through Inhibiting the Expression of lncTCF7
por: Li, Tengyu, et al.
Publicado: (2019)

Insights into Soluble Toll-Like Receptor 2 as a Downregulator of Virally Induced Inflammation
por: Henrick, Bethany M., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_jhfo5n9ovsee2rh95otnu8sapr