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In situ Proteomic Profiling of Curcumin Targets in HCT116 Colon Cancer Cell Line

To date, the exact targets and mechanism of action of curcumin, a natural product with anti-inflammatory and anti-cancer properties, remain elusive. Here we synthesized a cell permeable curcumin probe (Cur-P) with an alkyne moiety, which can be tagged with biotin for affinity enrichment, or with a f...

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Detalles Bibliográficos
Autores principales: Wang, Jigang, Zhang, Jianbin, Zhang, Chong-Jing, Wong, Yin Kwan, Lim, Teck Kwang, Hua, Zi-Chun, Liu, Bin, Tannenbaum, Steven R., Shen, Han-Ming, Lin, Qingsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768257/
https://www.ncbi.nlm.nih.gov/pubmed/26915414
http://dx.doi.org/10.1038/srep22146