Cargando…

Effects of local structural transformation of lipid-like compounds on delivery of messenger RNA

Lipid-like nanoparticles (LLNs) have shown great potential for RNA delivery. Lipid-like compounds are key components in LLNs. In this study, we investigated the effects of local structural transformation of lipid-like compounds on delivery of messenger RNA. Our results showed that position change of...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Bin, Luo, Xiao, Deng, Binbin, Giancola, JoLynn B., McComb, David W., Schmittgen, Thomas D., Dong, Yizhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768262/
https://www.ncbi.nlm.nih.gov/pubmed/26916931
http://dx.doi.org/10.1038/srep22137