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Effects of local structural transformation of lipid-like compounds on delivery of messenger RNA
Lipid-like nanoparticles (LLNs) have shown great potential for RNA delivery. Lipid-like compounds are key components in LLNs. In this study, we investigated the effects of local structural transformation of lipid-like compounds on delivery of messenger RNA. Our results showed that position change of...
Autores principales: | Li, Bin, Luo, Xiao, Deng, Binbin, Giancola, JoLynn B., McComb, David W., Schmittgen, Thomas D., Dong, Yizhou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768262/ https://www.ncbi.nlm.nih.gov/pubmed/26916931 http://dx.doi.org/10.1038/srep22137 |
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