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An Integrative Pharmacogenomic Approach Identifies Two-drug Combination Therapies for Personalized Cancer Medicine

An individual tumor harbors multiple molecular alterations that promote cell proliferation and prevent apoptosis and differentiation. Drugs that target specific molecular alterations have been introduced into personalized cancer medicine, but their effects can be modulated by the activities of other...

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Detalles Bibliográficos
Autores principales: Liu, Yin, Fei, Teng, Zheng, Xiaoqi, Brown, Myles, Zhang, Peng, Liu, X. Shirley, Wang, Haiyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768263/
https://www.ncbi.nlm.nih.gov/pubmed/26916442
http://dx.doi.org/10.1038/srep22120