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Frailty is associated with the epigenetic clock but not with telomere length in a German cohort

BACKGROUND: The epigenetic clock, in particular epigenetic pre-aging quantified by the so-called DNA methylation age acceleration, has recently been suggested to closely correlate with a variety of disease phenotypes. There remains a dearth of data, however, on its association with telomere length a...

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Detalles Bibliográficos
Autores principales: Breitling, Lutz Philipp, Saum, Kai-Uwe, Perna, Laura, Schöttker, Ben, Holleczek, Bernd, Brenner, Hermann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768341/
https://www.ncbi.nlm.nih.gov/pubmed/26925173
http://dx.doi.org/10.1186/s13148-016-0186-5