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Microglial brain region-dependent diversity and selective regional sensitivities to ageing

Microglia play critical roles in neural development, homeostasis and neuroinflammation and are increasingly implicated in age-related neurological dysfunction. Neurodegeneration often occurs in disease-specific spatially-restricted patterns, the origins of which are unknown. We performed the first g...

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Detalles Bibliográficos
Autores principales: Grabert, Kathleen, Michoel, Tom, Karavolos, Michail H, Clohisey, Sara, Baillie, J Kenneth, Stevens, Mark P, Freeman, Tom C, Summers, Kim M, McColl, Barry W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768346/
https://www.ncbi.nlm.nih.gov/pubmed/26780511
http://dx.doi.org/10.1038/nn.4222