Receptor tyrosine kinase‐like orphan receptor 1, a target of NKX2‐1/TTF‐1 lineage‐survival oncogene, inhibits apoptosis signal‐regulating kinase 1‐mediated pro‐apoptotic signaling in lung adenocarcinoma

We previously identified receptor tyrosine kinase‐like orphan receptor 1 (ROR1) as a transcriptional target of the NKX2‐1/TTF‐1 lineage‐survival oncogene in lung adenocarcinoma. ROR1 consequently sustains a favorable balance between pro‐survival phosphatidylinositol 3‐kinase–protein kinase B and pro...

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Detalles Bibliográficos
Autores principales: Ida, Lisa, Yamaguchi, Tomoya, Yanagisawa, Kiyoshi, Kajino, Taisuke, Shimada, Yukako, Suzuki, Motoshi, Takahashi, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768386/
https://www.ncbi.nlm.nih.gov/pubmed/26661061
http://dx.doi.org/10.1111/cas.12858

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768386/
https://www.ncbi.nlm.nih.gov/pubmed/26661061
http://dx.doi.org/10.1111/cas.12858

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