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Receptor tyrosine kinase‐like orphan receptor 1, a target of NKX2‐1/TTF‐1 lineage‐survival oncogene, inhibits apoptosis signal‐regulating kinase 1‐mediated pro‐apoptotic signaling in lung adenocarcinoma

We previously identified receptor tyrosine kinase‐like orphan receptor 1 (ROR1) as a transcriptional target of the NKX2‐1/TTF‐1 lineage‐survival oncogene in lung adenocarcinoma. ROR1 consequently sustains a favorable balance between pro‐survival phosphatidylinositol 3‐kinase–protein kinase B and pro...

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Detalles Bibliográficos
Autores principales:	Ida, Lisa, Yamaguchi, Tomoya, Yanagisawa, Kiyoshi, Kajino, Taisuke, Shimada, Yukako, Suzuki, Motoshi, Takahashi, Takashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768386/ https://www.ncbi.nlm.nih.gov/pubmed/26661061 http://dx.doi.org/10.1111/cas.12858

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