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Report on the use of non‐clinical studies in the regulatory evaluation of oncology drugs

This review summarizes the effective use of animal models, their advantages and disadvantages, ranges to be evaluated and limitations of the models currently used for the development and for the evaluation of oncology drugs.

Detalles Bibliográficos
Autores principales: Hayakawa, Yoshihiro, Kawada, Manabu, Nishikawa, Hiroyoshi, Ochiya, Takahiro, Saya, Hideyuki, Seimiya, Hiroyuki, Yao, Ryoji, Hayashi, Masahiro, Kai, Chieko, Matsuda, Akira, Naoe, Tomoki, Ohtsu, Atsushi, Okazaki, Taku, Saji, Hideo, Sata, Masataka, Sugimura, Haruhiko, Sugiyama, Yuichi, Toi, Masakazu, Irimura, Tatsuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768389/
https://www.ncbi.nlm.nih.gov/pubmed/26919617
http://dx.doi.org/10.1111/cas.12857