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Report on the use of non‐clinical studies in the regulatory evaluation of oncology drugs
This review summarizes the effective use of animal models, their advantages and disadvantages, ranges to be evaluated and limitations of the models currently used for the development and for the evaluation of oncology drugs.
Autores principales: | Hayakawa, Yoshihiro, Kawada, Manabu, Nishikawa, Hiroyoshi, Ochiya, Takahiro, Saya, Hideyuki, Seimiya, Hiroyuki, Yao, Ryoji, Hayashi, Masahiro, Kai, Chieko, Matsuda, Akira, Naoe, Tomoki, Ohtsu, Atsushi, Okazaki, Taku, Saji, Hideo, Sata, Masataka, Sugimura, Haruhiko, Sugiyama, Yuichi, Toi, Masakazu, Irimura, Tatsuro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768389/ https://www.ncbi.nlm.nih.gov/pubmed/26919617 http://dx.doi.org/10.1111/cas.12857 |
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