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A multiple testing procedure for multi-dimensional pairwise comparisons with application to gene expression studies
BACKGROUND: Often researchers are interested in comparing multiple experimental groups (e.g. tumor size) with a reference group (e.g. normal tissue) on the basis of thousands of features (e.g. genes) and determine if a differentially expressed feature is up or down regulated in a pairwise comparison...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768411/ https://www.ncbi.nlm.nih.gov/pubmed/26917217 http://dx.doi.org/10.1186/s12859-016-0937-5 |