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A multiple testing procedure for multi-dimensional pairwise comparisons with application to gene expression studies

BACKGROUND: Often researchers are interested in comparing multiple experimental groups (e.g. tumor size) with a reference group (e.g. normal tissue) on the basis of thousands of features (e.g. genes) and determine if a differentially expressed feature is up or down regulated in a pairwise comparison...

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Detalles Bibliográficos
Autores principales: Grandhi, Anjana, Guo, Wenge, Peddada, Shyamal D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768411/
https://www.ncbi.nlm.nih.gov/pubmed/26917217
http://dx.doi.org/10.1186/s12859-016-0937-5