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A prospective multicenter phase I/II clinical trial to evaluate safety and efficacy of NOVOCART Disc plus autologous disc chondrocyte transplantation in the treatment of nucleotomized and degenerative lumbar disc to avoid secondary disease: study protocol for a randomized controlled trial

BACKGROUND: Intervertebral disc degeneration is emphasized as an important cause of low back pain. Current surgical treatment provides relief to the accompanying pain and disability but does not restore the biological function of the intervertebral disc. NOVOCART™ Disc plus, an autologous cell compo...

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Detalles Bibliográficos
Autores principales: Tschugg, Anja, Michnacs, Felix, Strowitzki, Martin, Meisel, Hans Jörg, Thomé, Claudius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768412/
https://www.ncbi.nlm.nih.gov/pubmed/26920137
http://dx.doi.org/10.1186/s13063-016-1239-y