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A prospective multicenter phase I/II clinical trial to evaluate safety and efficacy of NOVOCART Disc plus autologous disc chondrocyte transplantation in the treatment of nucleotomized and degenerative lumbar disc to avoid secondary disease: study protocol for a randomized controlled trial
BACKGROUND: Intervertebral disc degeneration is emphasized as an important cause of low back pain. Current surgical treatment provides relief to the accompanying pain and disability but does not restore the biological function of the intervertebral disc. NOVOCART™ Disc plus, an autologous cell compo...
Autores principales: | Tschugg, Anja, Michnacs, Felix, Strowitzki, Martin, Meisel, Hans Jörg, Thomé, Claudius |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768412/ https://www.ncbi.nlm.nih.gov/pubmed/26920137 http://dx.doi.org/10.1186/s13063-016-1239-y |
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