Cargando…

Aberrant KDM5B expression promotes aggressive breast cancer through MALAT1 overexpression and downregulation of hsa-miR-448

BACKGROUND: Triple negative breast cancers (TNBC) possess cell dedifferentiation characteristics, carry out activities connate to those of cancer stem cells (CSCs) and are associated with increased metastasis, as well as, poor clinical prognosis. The regulatory mechanism of this highly malignant phe...

Descripción completa

Detalles Bibliográficos
Autores principales: Bamodu, Oluwaseun Adebayo, Huang, Wen-Chien, Lee, Wei-Hwa, Wu, Alexander, Wang, Liang Shun, Hsiao, Michael, Yeh, Chi-Tai, Chao, Tsu-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768424/
https://www.ncbi.nlm.nih.gov/pubmed/26917489
http://dx.doi.org/10.1186/s12885-016-2108-5