Cargando…

Aberrant KDM5B expression promotes aggressive breast cancer through MALAT1 overexpression and downregulation of hsa-miR-448

BACKGROUND: Triple negative breast cancers (TNBC) possess cell dedifferentiation characteristics, carry out activities connate to those of cancer stem cells (CSCs) and are associated with increased metastasis, as well as, poor clinical prognosis. The regulatory mechanism of this highly malignant phe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bamodu, Oluwaseun Adebayo, Huang, Wen-Chien, Lee, Wei-Hwa, Wu, Alexander, Wang, Liang Shun, Hsiao, Michael, Yeh, Chi-Tai, Chao, Tsu-Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768424/ https://www.ncbi.nlm.nih.gov/pubmed/26917489 http://dx.doi.org/10.1186/s12885-016-2108-5

Ejemplares similares

Histone demethylase JARID1B/KDM5B promotes aggressiveness of non-small cell lung cancer and serves as a good prognostic predictor
por: Kuo, Kuang-Tai, et al.
Publicado: (2018)

MiR-448 promotes glycolytic metabolism of gastric cancer by downregulating KDM2B
por: Hong, Xuehui, et al.
Publicado: (2016)

Targeting the Epigenetic Non-Coding RNA MALAT1/Wnt Signaling Axis as a Therapeutic Approach to Suppress Stemness and Metastasis in Hepatocellular Carcinoma
por: Chang, Hang-Lung, et al.
Publicado: (2020)

MED10 Drives the Oncogenicity and Refractory Phenotype of Bladder Urothelial Carcinoma Through the Upregulation of hsa-miR-590
por: Wu, Chia-Chang, et al.
Publicado: (2022)

Cadherin 11 Inhibition Downregulates β-catenin, Deactivates the Canonical WNT Signalling Pathway and Suppresses the Cancer Stem Cell-Like Phenotype of Triple Negative Breast Cancer
por: Satriyo, Pamungkas Bagus, et al.
Publicado: (2019)

4-Acetyl-Antroquinonol B Suppresses SOD2-Enhanced Cancer Stem Cell-Like Phenotypes and Chemoresistance of Colorectal Cancer Cells by Inducing hsa-miR-324 re-Expression
por: Bamodu, Oluwaseun Adebayo, et al.
Publicado: (2018)

Combined Treatment with Acalabrutinib and Rapamycin Inhibits Glioma Stem Cells and Promotes Vascular Normalization by Downregulating BTK/mTOR/VEGF Signaling
por: Su, Yu-Kai, et al.
Publicado: (2021)

Enhanced Hsa-miR-181d/p-STAT3 and Hsa-miR-181d/p-STAT5A Ratios Mediate the Anticancer Effect of Garcinol in STAT3/5A-Addicted Glioblastoma
por: Liu, Heng-Wei, et al.
Publicado: (2019)

Targeted PARP Inhibition Combined with FGFR1 Blockade is Synthetically Lethal to Malignant Cells in Patients with Pancreatic Cancer
por: Lai, Shiue-Wei, et al.
Publicado: (2020)

Exosomal lncRNA PVT1/VEGFA Axis Promotes Colon Cancer Metastasis and Stemness by Downregulation of Tumor Suppressor miR-152-3p
por: Lai, Shiue-Wei, et al.
Publicado: (2021)

Correction: Liu, H.W.; et al. Enhanced Hsa-miR-181d/p-STAT3 and Hsa-miR-181d/p-STAT5A Ratios Mediate the Anticancer Effect of Garcinol in STAT3/5A-Addicted Glioblastoma. Cancers 2019, 11, 1888
por: Liu, Heng-Wei, et al.
Publicado: (2020)

Insulin Resistance Promotes Parkinson’s Disease through Aberrant Expression of α-Synuclein, Mitochondrial Dysfunction, and Deregulation of the Polo-Like Kinase 2 Signaling
por: Hong, Chien-Tai, et al.
Publicado: (2020)

Targeting FAT1 Inhibits Carcinogenesis, Induces Oxidative Stress and Enhances Cisplatin Sensitivity through Deregulation of LRP5/WNT2/GSS Signaling Axis in Oral Squamous Cell Carcinoma
por: Hsu, Tung-Nien, et al.
Publicado: (2019)

Elevated PDK1 Expression Drives PI3K/AKT/MTOR Signaling Promotes Radiation-Resistant and Dedifferentiated Phenotype of Hepatocellular Carcinoma
por: Bamodu, Oluwaseun Adebayo, et al.
Publicado: (2020)

A cross-country comparison of malaria policy as a premise for contextualized appropriation of foreign aid in global health
por: Jezek, Tomas, et al.
Publicado: (2021)

JARID1B Expression Plays a Critical Role in Chemoresistance and Stem Cell-Like Phenotype of Neuroblastoma Cells
por: Kuo, Yung-Ting, et al.
Publicado: (2015)

SUMO-Activating Enzyme Subunit 1 (SAE1) Is a Promising Diagnostic Cancer Metabolism Biomarker of Hepatocellular Carcinoma
por: Ong, Jiann Ruey, et al.
Publicado: (2021)

CD47-SIRPα Signaling Induces Epithelial-Mesenchymal Transition and Cancer Stemness and Links to a Poor Prognosis in Patients with Oral Squamous Cell Carcinoma
por: Pai, Shin, et al.
Publicado: (2019)

Post-valvular surgery multi-vessel coronary artery spasm — A literature review
por: Formica, Francesco, et al.
Publicado: (2015)

KDM5B promotes self‐renewal of hepatocellular carcinoma cells through the microRNA‐448–mediated YTHDF3/ITGA6 axis
por: Guo, Jun‐Cheng, et al.
Publicado: (2021)

Artificial neural network based prediction of postthrombolysis intracerebral hemorrhage and death
por: Chung, Chen-Chih, et al.
Publicado: (2020)

Neurofilament light chain level in plasma extracellular vesicles and Parkinson’s disease
por: Chung, Chen-Chih, et al.
Publicado: (2020)

Blood Neurofilament Light Chain in Parkinson’s Disease: Comparability between Parkinson’s Progression Markers Initiative (PPMI) and Asian Cohorts
por: Chen, Jia-Hung, et al.
Publicado: (2021)

Astragalus polysaccharide (PG2) Ameliorates Cancer Symptom Clusters, as well as Improves Quality of Life in Patients with Metastatic Disease, through Modulation of the Inflammatory Cascade
por: Huang, Wen-Chien, et al.
Publicado: (2019)

Monospecific antibody targeting of CDH11 inhibits epithelial-to-mesenchymal transition and represses cancer stem cell-like phenotype by up-regulating miR-335 in metastatic breast cancer, in vitro and in vivo
por: Chen, Jia-Hong, et al.
Publicado: (2019)

Ovatodiolide Suppresses Oral Cancer Malignancy by Down-Regulating Exosomal Mir-21/STAT3/β-Catenin Cargo and Preventing Oncogenic Transformation of Normal Gingival Fibroblasts
por: Chen, Jia-Hong, et al.
Publicado: (2019)

The Disruption of the β-Catenin/TCF-1/STAT3 Signaling Axis by 4-Acetylantroquinonol B Inhibits the Tumorigenesis and Cancer Stem-Cell-Like Properties of Glioblastoma Cells, In Vitro and In Vivo
por: Liu, Heng-Wei, et al.
Publicado: (2018)

Astragalus polysaccharides (PG2) Enhances the M1 Polarization of Macrophages, Functional Maturation of Dendritic Cells, and T Cell-Mediated Anticancer Immune Responses in Patients with Lung Cancer
por: Bamodu, Oluwaseun Adebayo, et al.
Publicado: (2019)

A Novel Multi-Target Small Molecule, LCC-09, Inhibits Stemness and Therapy-Resistant Phenotypes of Glioblastoma Cells by Increasing miR-34a and Deregulating the DRD4/Akt/mTOR Signaling Axis
por: Wen, Ya-Ting, et al.
Publicado: (2019)

Extracorporeal Shockwave Therapy (ESWT) Alleviates Pain, Enhances Erectile Function and Improves Quality of Life in Patients with Chronic Prostatitis/Chronic Pelvic Pain Syndrome
por: Wu, Wen-Ling, et al.
Publicado: (2021)

Collagen 1A1 (COL1A1) Is a Reliable Biomarker and Putative Therapeutic Target for Hepatocellular Carcinogenesis and Metastasis
por: Ma, Hon-Ping, et al.
Publicado: (2019)

lnc-IL7R Expression Reflects Physiological Pulmonary Function and Its Aberration Is a Putative Indicator of COPD
por: Bamodu, Oluwaseun Adebayo, et al.
Publicado: (2022)

The aberrant overexpression of vimentin is linked to a more aggressive status in tumours of the gastrointestinal tract
por: Brzozowa, Marlena, et al.
Publicado: (2015)

Artificial neural network-boosted Cardiac Arrest Survival Post-Resuscitation In-hospital (CASPRI) score accurately predicts outcome in cardiac arrest patients treated with targeted temperature management
por: Chou, Szu-Yi, et al.
Publicado: (2022)

Concomitant High Apoptosis Inhibitor of Macrophage (AIM) and Low Prostate-Specific Antigen (PSA) Indicates Activated T Cell-Mediated Anticancer Immunity, Enhance Sensitivity to Pembrolizumab, and Elicit Good Prognosis in Prostate Cancer
por: Bamodu, Oluwaseun Adebayo, et al.
Publicado: (2021)

Sonata in D major K. 448 Andante mit Variationen K. 501 /
por: Mozart, Wolfgang Amadeus, 1756-1791
Publicado: (1993)

MALAT1-dependent hsa_circ_0076611 regulates translation rate in triple-negative breast cancer
por: Turco, Chiara, et al.
Publicado: (2022)

Downregulation of microRNA-448 inhibits IL-1β-induced cartilage degradation in human chondrocytes via upregulation of matrilin-3
por: Yang, Hao, et al.
Publicado: (2018)

Risk factor identification and prediction models for prolonged length of stay in hospital after acute ischemic stroke using artificial neural networks
por: Yang, Cheng-Chang, et al.
Publicado: (2023)

448. Can Electronic Clinical Notes Identify Travelers with Zika?
por: Peterson, Kelly, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_77r4otjhs579rgtl5rqrl6s0sq