Pyrrolidine dithiocarbamate activates the Nrf2 pathway in astrocytes

BACKGROUND: Endogenous defense against oxidative stress is controlled by nuclear factor erythroid 2-related factor 2 (Nrf2). The normal compensatory mechanisms to combat oxidative stress appear to be insufficient to protect against the prolonged exposure to reactive oxygen species during disease. Co...

Descripción completa

Detalles Bibliográficos
Autores principales: Liddell, Jeffrey R., Lehtonen, Sarka, Duncan, Clare, Keksa-Goldsteine, Velta, Levonen, Anna-Liisa, Goldsteins, Gundars, Malm, Tarja, White, Anthony R., Koistinaho, Jari, Kanninen, Katja M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768425/
https://www.ncbi.nlm.nih.gov/pubmed/26920699
http://dx.doi.org/10.1186/s12974-016-0515-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768425/
https://www.ncbi.nlm.nih.gov/pubmed/26920699
http://dx.doi.org/10.1186/s12974-016-0515-9

Ejemplares similares