Alteration of the DNA methylation status of donor cells impairs the developmental competence of porcine cloned embryos

Nuclear reprogramming induced by somatic cell nuclear transfer is an inefficient process, and donor cell DNA methylation status is thought to be a major factor affecting cloning efficiency. Here, the role of donor cell DNA methylation status regulated by 5-aza-2'-deoxycytidine (5-aza-dC) or 5-m...

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Detalles Bibliográficos
Autores principales: HUAN, Yan Jun, WU, Zhan Feng, ZHANG, Ji Guang, ZHU, Jiang, XIE, Bing Teng, WANG, Jian Yu, LI, Jing Yu, XUE, Bing Hua, KONG, Qing Ran, LIU, Zhong Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Society for Reproduction and Development 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768780/
https://www.ncbi.nlm.nih.gov/pubmed/26537205
http://dx.doi.org/10.1262/jrd.2015-048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768780/
https://www.ncbi.nlm.nih.gov/pubmed/26537205
http://dx.doi.org/10.1262/jrd.2015-048

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