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Knockout mouse production assisted by Blm knockdown

Production of knockout mice using targeted embryonic stem cells (ESCs) is a powerful approach for investigating the function of specific genes in vivo. Although the protocol for gene targeting via homologous recombination (HR) in ESCs is already well established, the targeting efficiency varies at d...

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Detalles Bibliográficos
Autores principales: FUKUDA, Mikiko, INOUE, Mayuko, MURAMATSU, Daisuke, MIYACHI, Hitoshi, SHINKAI, Yoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Society for Reproduction and Development 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768786/
https://www.ncbi.nlm.nih.gov/pubmed/26598326
http://dx.doi.org/10.1262/jrd.2015-122