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A Simple Model to Study Tau Pathology

Tau proteins play a role in the stabilization of microtubules, but in pathological conditions, tauopathies, tau is modified by phosphorylation and can aggregate into aberrant aggregates. These aggregates could be toxic to cells, and different cell models have been used to test for compounds that mig...

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Detalles Bibliográficos
Autores principales: Houck, Alexander L., Hernández, Félix, Ávila, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768941/
https://www.ncbi.nlm.nih.gov/pubmed/26949341
http://dx.doi.org/10.4137/JEN.S25100