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A Simple Model to Study Tau Pathology
Tau proteins play a role in the stabilization of microtubules, but in pathological conditions, tauopathies, tau is modified by phosphorylation and can aggregate into aberrant aggregates. These aggregates could be toxic to cells, and different cell models have been used to test for compounds that mig...
Autores principales: | Houck, Alexander L., Hernández, Félix, Ávila, Jesús |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Libertas Academica
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768941/ https://www.ncbi.nlm.nih.gov/pubmed/26949341 http://dx.doi.org/10.4137/JEN.S25100 |
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