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Detection of Productively Rearranged TcR-α V–J Sequences in TCGA Exome Files: Implications for Tumor Immunoscoring and Recovery of Antitumor T-cells

Tumor immunoscoring is rapidly becoming a universal parameter of prognosis, and T-cells isolated from tumor masses are used for ex vivo amplification and readministration to patients to facilitate an antitumor immune response. We recently exploited the cancer genome atlas (TCGA) RNASeq data to asses...

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Detalles Bibliográficos
Autores principales: Gill, Thomas R., Samy, Mohammad D., Butler, Shanitra N., Mauro, James A., Sexton, Wade J., Blanck, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768948/
https://www.ncbi.nlm.nih.gov/pubmed/26966347
http://dx.doi.org/10.4137/CIN.S35784