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Inhibition of Rho-associated protein kinase increases the ratio of formation of blastocysts from single human blastomeres

Y-27632 is a specific inhibitor of Rho-associated protein kinases (ROCKs), which are downstream effectors of Rho GTPase. The present study aimed to determine the effect of the specific ROCK inhibitor, Y-27632, on fresh human embryos and on single blastomeres obtained from discarded human embryos. A...

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Detalles Bibliográficos
Autores principales: HUANG, SUNXING, DING, CHENHUI, MAI, QINGYUN, XU, YANWEN, ZHOU, CANQUAN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768968/
https://www.ncbi.nlm.nih.gov/pubmed/26783117
http://dx.doi.org/10.3892/mmr.2016.4766