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Targeting of cancer-associated fibroblasts enhances the efficacy of cancer chemotherapy by regulating the tumor microenvironment

Cancer-associated fibroblasts (CAFs), key components of the tumor stroma, can regulate tumorigenesis by altering the tumor microenvironment in variety of ways to promote angiogenesis, recruit inflammatory immune cells and remodel the extracellular matrix. Using a murine xenograft model of colon carc...

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Detalles Bibliográficos
Autores principales: LI, MINMIN, LI, MEI, YIN, TAO, SHI, HUASHAN, WEN, YUAN, ZHANG, BINGLAN, CHEN, MEIHUA, XU, GUANGCHAO, REN, KEXIN, WEI, YUQUAN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768992/
https://www.ncbi.nlm.nih.gov/pubmed/26846566
http://dx.doi.org/10.3892/mmr.2016.4868