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Metformin inhibits growth of human non-small cell lung cancer cells via liver kinase B-1-independent activation of adenosine monophosphate-activated protein kinase

Metformin, the most widely administered oral anti-diabetic therapeutic agent, exerts its glucose-lowering effect predominantly via liver kinase B1 (LKB1)-dependent activation of adenosine monophosphate-activated protein kinase (AMPK). Accumulating evidence has demonstrated that metformin possesses p...

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Detalles Bibliográficos
Autores principales: GUO, QIANQIAN, LIU, ZHIYAN, JIANG, LILI, LIU, MENGJIE, MA, JIEQUN, YANG, CHENGCHENG, HAN, LILI, NAN, KEJUN, LIANG, XUAN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768996/
https://www.ncbi.nlm.nih.gov/pubmed/26847819
http://dx.doi.org/10.3892/mmr.2016.4830