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Genotype-phenotype analysis of CYP2C19 in the Tibetan population and its potential clinical implications in drug therapy

Cytochrome P450 2C19 (CYP2C19) is a highly polymorphic gene, it codes for a protein responsible for the metabolism of multiple clinically important therapeutic agents. However, there is currently no available data on the distribution of CYP2C19 mutant alleles in the Tibetan population. The aim of th...

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Detalles Bibliográficos
Autores principales: JIN, TIANBO, ZHANG, XIYANG, GENG, TINGTING, SHI, XUGANG, WANG, LI, YUAN, DONGYA, KANG, LONGLI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768997/
https://www.ncbi.nlm.nih.gov/pubmed/26781306
http://dx.doi.org/10.3892/mmr.2016.4776