Folic acid reverses uric acid crystal-induced surface OAT1 internalization by inhibiting RhoA activity in uric acid nephropathy

To investigate how organic anion transporter (OAT)-1 is involved in uric acid nephropathy (UAN), a rat model for UAN was established and the serum uric acid, blood urea nitrogen and serum creatinine levels were all measured, and observed to be increased. It was additionally identified that in UAN ra...

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Detalles Bibliográficos
Autores principales: WU, XINLIN, LIU, JIANXIANG, ZHANG, JIANQING, LIU, HENG, YAN, MIANSHENG, LIANG, BIRONG, XIE, HONGBO, ZHANG, SHIJUN, SUN, BAOGUO, ZHOU, HOUMING
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768998/
https://www.ncbi.nlm.nih.gov/pubmed/26846716
http://dx.doi.org/10.3892/mmr.2016.4837

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768998/
https://www.ncbi.nlm.nih.gov/pubmed/26846716
http://dx.doi.org/10.3892/mmr.2016.4837

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