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Solar Simulated Ultraviolet Radiation Induces Global Histone Hypoacetylation in Human Keratinocytes

Ultraviolet radiation (UVR) from sunlight is the primary effector of skin DNA damage. Chromatin remodeling and histone post-translational modification (PTM) are critical factors in repairing DNA damage and maintaining genomic integrity, however, the dynamic changes of histone marks in response to so...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoru, Kluz, Thomas, Gesumaria, Lisa, Matsui, Mary S., Costa, Max, Sun, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769140/
https://www.ncbi.nlm.nih.gov/pubmed/26918332
http://dx.doi.org/10.1371/journal.pone.0150175