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Solar Simulated Ultraviolet Radiation Induces Global Histone Hypoacetylation in Human Keratinocytes
Ultraviolet radiation (UVR) from sunlight is the primary effector of skin DNA damage. Chromatin remodeling and histone post-translational modification (PTM) are critical factors in repairing DNA damage and maintaining genomic integrity, however, the dynamic changes of histone marks in response to so...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769140/ https://www.ncbi.nlm.nih.gov/pubmed/26918332 http://dx.doi.org/10.1371/journal.pone.0150175 |