Ion Channel Blockers as Antimicrobial Agents, Efflux Inhibitors, and Enhancers of Macrophage Killing Activity against Drug Resistant Mycobacterium tuberculosis

Given the ability of M. tuberculosis to survive as an intracellular pathogen and its propensity to develop resistance to the existing antituberculosis drugs, its treatment requires new approaches. Here the antimycobacterial properties of verapamil, thioridazine, chlorpromazine, flupenthixol and halo...

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Detalles Bibliográficos
Autores principales: Machado, Diana, Pires, David, Perdigão, João, Couto, Isabel, Portugal, Isabel, Martins, Marta, Amaral, Leonard, Anes, Elsa, Viveiros, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769142/
https://www.ncbi.nlm.nih.gov/pubmed/26919135
http://dx.doi.org/10.1371/journal.pone.0149326

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769142/
https://www.ncbi.nlm.nih.gov/pubmed/26919135
http://dx.doi.org/10.1371/journal.pone.0149326

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