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Ion Channel Blockers as Antimicrobial Agents, Efflux Inhibitors, and Enhancers of Macrophage Killing Activity against Drug Resistant Mycobacterium tuberculosis
Given the ability of M. tuberculosis to survive as an intracellular pathogen and its propensity to develop resistance to the existing antituberculosis drugs, its treatment requires new approaches. Here the antimycobacterial properties of verapamil, thioridazine, chlorpromazine, flupenthixol and halo...
Autores principales: | Machado, Diana, Pires, David, Perdigão, João, Couto, Isabel, Portugal, Isabel, Martins, Marta, Amaral, Leonard, Anes, Elsa, Viveiros, Miguel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769142/ https://www.ncbi.nlm.nih.gov/pubmed/26919135 http://dx.doi.org/10.1371/journal.pone.0149326 |
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