The Functional Significance of Posttranslational Modifications on Polo-Like Kinase 1 Revealed by Chemical Genetic Complementation

Mitosis is coordinated by carefully controlled phosphorylation and ubiquitin-mediated proteolysis. Polo-like kinase 1 (Plk1) plays a central role in regulating mitosis and cytokinesis by phosphorylating target proteins. Yet, Plk1 is itself a target for posttranslational modification by phosphorylati...

Descripción completa

Detalles Bibliográficos
Autores principales: Lasek, Amber L., McPherson, Brittany M., Trueman, Natalie G., Burkard, Mark E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769148/
https://www.ncbi.nlm.nih.gov/pubmed/26919439
http://dx.doi.org/10.1371/journal.pone.0150225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769148/
https://www.ncbi.nlm.nih.gov/pubmed/26919439
http://dx.doi.org/10.1371/journal.pone.0150225

Ejemplares similares