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Stepwise nucleosome translocation by RSC remodeling complexes

The SWI/SNF-family remodelers regulate chromatin structure by coupling the free energy from ATP hydrolysis to the repositioning and restructuring of nucleosomes, but how the ATPase activity of these enzymes drives the motion of DNA across the nucleosome remains unclear. Here, we used single-molecule...

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Detalles Bibliográficos
Autores principales: Harada, Bryan T, Hwang, William L, Deindl, Sebastian, Chatterjee, Nilanjana, Bartholomew, Blaine, Zhuang, Xiaowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769157/
https://www.ncbi.nlm.nih.gov/pubmed/26895087
http://dx.doi.org/10.7554/eLife.10051