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Lipoprotein X Causes Renal Disease in LCAT Deficiency

Human familial lecithin:cholesterol acyltransferase (LCAT) deficiency (FLD) is characterized by low HDL, accumulation of an abnormal cholesterol-rich multilamellar particle called lipoprotein-X (LpX) in plasma, and renal disease. The aim of our study was to determine if LpX is nephrotoxic and to gai...

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Detalles Bibliográficos
Autores principales: Ossoli, Alice, Neufeld, Edward B., Thacker, Seth G., Vaisman, Boris, Pryor, Milton, Freeman, Lita A., Brantner, Christine A., Baranova, Irina, Francone, Nicolás O., Demosky, Stephen J., Vitali, Cecilia, Locatelli, Monica, Abbate, Mauro, Zoja, Carlamaria, Franceschini, Guido, Calabresi, Laura, Remaley, Alan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769176/
https://www.ncbi.nlm.nih.gov/pubmed/26919698
http://dx.doi.org/10.1371/journal.pone.0150083