Cargando…

An epigenetic switch ensures transposon repression upon dynamic loss of DNA methylation in embryonic stem cells

DNA methylation is extensively remodeled during mammalian gametogenesis and embryogenesis. Most transposons become hypomethylated, raising the question of their regulation in the absence of DNA methylation. To reproduce a rapid and extensive demethylation, we subjected mouse ES cells to chemically d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Walter, Marius, Teissandier, Aurélie, Pérez-Palacios, Raquel, Bourc'his, Déborah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2016
Materias:	Developmental Biology and Stem Cells
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769179/ https://www.ncbi.nlm.nih.gov/pubmed/26814573 http://dx.doi.org/10.7554/eLife.11418

Ejemplares similares

Assessing the influence of distinct culture media on human pre-implantation development using single-embryo transcriptomics
por: Ducreux, Bastien, et al.
Publicado: (2023)

DNA methylation restrains transposons from adopting a chromatin signature permissive for meiotic recombination
por: Zamudio, Natasha, et al.
Publicado: (2015)

Dynamic enhancer partitioning instructs activation of a growth-related gene during exit from naïve pluripotency
por: Greenberg, Maxim, et al.
Publicado: (2019)

Tools and best practices for retrotransposon analysis using high-throughput sequencing data
por: Teissandier, Aurélie, et al.
Publicado: (2019)

H3K9 tri-methylation at Nanog times differentiation commitment and enables the acquisition of primitive endoderm fate
por: Dubois, Agnès, et al.
Publicado: (2022)

The discovery and importance of genomic imprinting
por: Ferguson-Smith, Anne C, et al.
Publicado: (2018)

Global reorganisation of cis-regulatory units upon lineage commitment of human embryonic stem cells
por: Freire-Pritchett, Paula, et al.
Publicado: (2017)

The imprinted Zdbf2 gene finely tunes control of feeding and growth in neonates
por: Glaser, Juliane, et al.
Publicado: (2022)

The Apelin receptor enhances Nodal/TGFβ signaling to ensure proper cardiac development
por: Deshwar, Ashish R, et al.
Publicado: (2016)

Tips from the embryonic lung
por: Waghray, Avinash, et al.
Publicado: (2017)

Hox genes control vertebrate body elongation by collinear Wnt repression
por: Denans, Nicolas, et al.
Publicado: (2015)

Dynamic Evolution of De Novo DNA Methyltransferases in Rodent and Primate Genomes
por: Molaro, Antoine, et al.
Publicado: (2020)

Endogenous retroviral insertions drive non-canonical imprinting in extra-embryonic tissues
por: Hanna, Courtney W., et al.
Publicado: (2019)

Epigenetic regulation of hematopoiesis by DNA methylation
por: Gore, Aniket V, et al.
Publicado: (2016)

MicroRNA-203 represses selection and expansion of oncogenic Hras transformed tumor initiating cells
por: Riemondy, Kent, et al.
Publicado: (2015)

The REST remodeling complex protects genomic integrity during embryonic neurogenesis
por: Nechiporuk, Tamilla, et al.
Publicado: (2016)

Foxc1 dependent mesenchymal signalling drives embryonic cerebellar growth
por: Haldipur, Parthiv, et al.
Publicado: (2014)

The transcription factor Pitx2 positions the embryonic axis and regulates twinning
por: Torlopp, Angela, et al.
Publicado: (2014)

Embryonic origin of adult stem cells required for tissue homeostasis and regeneration
por: Davies, Erin L, et al.
Publicado: (2017)

Polycomb enables primitive endoderm lineage priming in embryonic stem cells
por: Illingworth, Robert S, et al.
Publicado: (2016)

AIRE is a critical spindle-associated protein in embryonic stem cells
por: Gu, Bin, et al.
Publicado: (2017)

FGF/MAPK signaling sets the switching threshold of a bistable circuit controlling cell fate decisions in embryonic stem cells
por: Schröter, Christian, et al.
Publicado: (2015)

Histone demethylase Lsd1 represses hematopoietic stem and progenitor cell signatures during blood cell maturation
por: Kerenyi, Marc A, et al.
Publicado: (2013)

Dual mode of embryonic development is highlighted by expression and function of Nasonia pair-rule genes
por: Rosenberg, Miriam I, et al.
Publicado: (2014)

Logics and properties of a genetic regulatory program that drives embryonic muscle development in an echinoderm
por: Andrikou, Carmen, et al.
Publicado: (2015)

Intracellular uptake of macromolecules by brain lymphatic endothelial cells during zebrafish embryonic development
por: van Lessen, Max, et al.
Publicado: (2017)

Sugar promotes vegetative phase change in Arabidopsis thaliana by repressing the expression of MIR156A and MIR156C
por: Yang, Li, et al.
Publicado: (2013)

Requirement for highly efficient pre-mRNA splicing during Drosophila early embryonic development
por: Guilgur, Leonardo Gastón, et al.
Publicado: (2014)

DNA methylation directs genomic localization of Mbd2 and Mbd3 in embryonic stem cells
por: Hainer, Sarah J, et al.
Publicado: (2016)

Mobilization of LINE-1 retrotransposons is restricted by Tex19.1 in mouse embryonic stem cells
por: MacLennan, Marie, et al.
Publicado: (2017)

Elevated O‐GlcNAc Levels Activate Epigenetically Repressed Genes and Delay Mouse ESC Differentiation Without Affecting Naïve to Primed Cell Transition
por: Speakman, Christopher M., et al.
Publicado: (2014)

Mof-associated complexes have overlapping and unique roles in regulating pluripotency in embryonic stem cells and during differentiation
por: Ravens, Sarina, et al.
Publicado: (2014)

Essential role of lncRNA binding for WDR5 maintenance of active chromatin and embryonic stem cell pluripotency
por: Yang, Yul W, et al.
Publicado: (2014)

The CUL4-DDB1 ubiquitin ligase complex controls adult and embryonic stem cell differentiation and homeostasis
por: Gao, Jie, et al.
Publicado: (2015)

Area-specific development of distinct projection neuron subclasses is regulated by postnatal epigenetic modifications
por: Harb, Kawssar, et al.
Publicado: (2016)

Human embryonic lung epithelial tips are multipotent progenitors that can be expanded in vitro as long-term self-renewing organoids
por: Nikolić, Marko Z, et al.
Publicado: (2017)

Transcriptome Characterization of Repressed Embryonic Myogenesis Due to Maternal Calorie Restriction
por: He, Jun, et al.
Publicado: (2020)

Dissection of zebrafish shha function using site-specific targeting with a Cre-dependent genetic switch
por: Sugimoto, Kotaro, et al.
Publicado: (2017)

Embryonic attenuated Wnt/β-catenin signaling defines niche location and long-term stem cell fate in hair follicle
por: Xu, Zijian, et al.
Publicado: (2015)

Spatially resolved RNA-sequencing of the embryonic heart identifies a role for Wnt/β-catenin signaling in autonomic control of heart rate
por: Burkhard, Silja Barbara, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_o11hak369m4o9gt45k6tek44ur