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Monomeric Amyloid Beta Peptide in Hexafluoroisopropanol Detected by Small Angle Neutron Scattering

Small proteins like amyloid beta (Aβ) monomers are related to neurodegenerative disorders by aggregation to insoluble fibrils. Small angle neutron scattering (SANS) is a nondestructive method to observe the aggregation process in solution. We show that SANS is able to resolve monomers of small molec...

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Detalles Bibliográficos
Autores principales: Zhang-Haagen, Bo, Biehl, Ralf, Nagel-Steger, Luitgard, Radulescu, Aurel, Richter, Dieter, Willbold, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769228/
https://www.ncbi.nlm.nih.gov/pubmed/26919121
http://dx.doi.org/10.1371/journal.pone.0150267