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An intrapleural administration of zoledronic acid for inoperable malignant mesothelioma patients: a phase I clinical study protocol

BACKGROUND: The third generation of bisphosphonates is clinically in use for patients of osteoporosis or malignancy-linked hypercalcemia. The agents can also produce anti-tumor effects on bone metastasis of several types of tumors. We recently found that one of the agents achieved cytotoxicity to me...

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Detalles Bibliográficos
Autores principales: Tada, Yuji, Hiroshima, Kenzo, Shimada, Hideaki, Shingyoji, Masato, Suzuki, Toshio, Umezawa, Hiroki, Sekine, Ikuo, Takiguchi, Yuichi, Tatsumi, Koichiro, Tagawa, Masatoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769234/
https://www.ncbi.nlm.nih.gov/pubmed/27026891
http://dx.doi.org/10.1186/s40064-016-1893-2