Fluid-induced, shear stress-regulated extracellular matrix and matrix metalloproteinase genes expression on human annulus fibrosus cells

BACKGROUND: Mechanical loading plays an important role in the regulation of extracellular matrix (ECM) homeostasis as well as pathogenesis of intervertebral disc (IVD) degeneration. The human annulus fibrosus (hAF) in the IVD is subjected to contact shear stress during body motion. However, the effe...

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Detalles Bibliográficos
Autores principales: Chou, Po-Hsin, Wang, Shih-Tien, Yen, Meng-Hua, Liu, Chien-Lin, Chang, Ming-Chau, Lee, Oscar Kuang-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769486/
https://www.ncbi.nlm.nih.gov/pubmed/26921206
http://dx.doi.org/10.1186/s13287-016-0292-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769486/
https://www.ncbi.nlm.nih.gov/pubmed/26921206
http://dx.doi.org/10.1186/s13287-016-0292-5

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