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GATA3-dependent cellular reprogramming requires activation-domain dependent recruitment of a chromatin remodeler
BACKGROUND: Transcription factor-dependent cellular reprogramming is integral to normal development and is central to production of induced pluripotent stem cells. This process typically requires pioneer transcription factors (TFs) to induce de novo formation of enhancers at previously closed chroma...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769547/ https://www.ncbi.nlm.nih.gov/pubmed/26922637 http://dx.doi.org/10.1186/s13059-016-0897-0 |