GATA3-dependent cellular reprogramming requires activation-domain dependent recruitment of a chromatin remodeler

BACKGROUND: Transcription factor-dependent cellular reprogramming is integral to normal development and is central to production of induced pluripotent stem cells. This process typically requires pioneer transcription factors (TFs) to induce de novo formation of enhancers at previously closed chroma...

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Detalles Bibliográficos
Autores principales: Takaku, Motoki, Grimm, Sara A., Shimbo, Takashi, Perera, Lalith, Menafra, Roberta, Stunnenberg, Hendrik G., Archer, Trevor K., Machida, Shinichi, Kurumizaka, Hitoshi, Wade, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769547/
https://www.ncbi.nlm.nih.gov/pubmed/26922637
http://dx.doi.org/10.1186/s13059-016-0897-0

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