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Production of the forskolin precursor 11β-hydroxy-manoyl oxide in yeast using surrogate enzymatic activities
BACKGROUND: Several plant diterpenes have important biological properties. Among them, forskolin is a complex labdane-type diterpene whose biological activity stems from its ability to activate adenylyl cyclase and to elevate intracellular cAMP levels. As such, it is used in the control of blood pre...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769550/ https://www.ncbi.nlm.nih.gov/pubmed/26920948 http://dx.doi.org/10.1186/s12934-016-0440-8 |