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Betulinic acid enhances TGF-β signaling by altering TGF-β receptors partitioning between lipid-raft/caveolae and non-caveolae membrane microdomains in mink lung epithelial cells

BACKGROUND: TGF-β is a key modulator in the regulation of cell proliferation and migration, and is also involved in the process of cancer development and progression. Previous studies have indicated that TGF-β responsiveness is determined by TGF-β receptor partitioning between lipid raft/caveolae-me...

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Detalles Bibliográficos
Autores principales: Chen, C. L., Chen, C. Y., Chen, Y. P., Huang, Y. B., Lin, M. W., Wu, D. C., Huang, H. T., Liu, M. Y., Chang, H. W., Kao, Y. C., Yang, P. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769553/
https://www.ncbi.nlm.nih.gov/pubmed/26922801
http://dx.doi.org/10.1186/s12929-016-0229-4