Inferential considerations for low-count RNA-seq transcripts: a case study on the dominant prairie grass Andropogon gerardii

BACKGROUND: Differential expression (DE) analysis of RNA-seq data still poses inferential challenges, such as handling of transcripts characterized by low expression levels. In this study, we use a plasmode-based approach to assess the relative performance of alternative inferential strategies on RN...

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Detalles Bibliográficos
Autores principales: Raithel, Seth, Johnson, Loretta, Galliart, Matthew, Brown, Sue, Shelton, Jennifer, Herndon, Nicolae, Bello, Nora M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769568/
https://www.ncbi.nlm.nih.gov/pubmed/26919855
http://dx.doi.org/10.1186/s12864-016-2442-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769568/
https://www.ncbi.nlm.nih.gov/pubmed/26919855
http://dx.doi.org/10.1186/s12864-016-2442-7

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