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Inferential considerations for low-count RNA-seq transcripts: a case study on the dominant prairie grass Andropogon gerardii
BACKGROUND: Differential expression (DE) analysis of RNA-seq data still poses inferential challenges, such as handling of transcripts characterized by low expression levels. In this study, we use a plasmode-based approach to assess the relative performance of alternative inferential strategies on RN...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769568/ https://www.ncbi.nlm.nih.gov/pubmed/26919855 http://dx.doi.org/10.1186/s12864-016-2442-7 |