Exploiting biological priors and sequence variants enhances QTL discovery and genomic prediction of complex traits

BACKGROUND: Dense SNP genotypes are often combined with complex trait phenotypes to map causal variants, study genetic architecture and provide genomic predictions for individuals with genotypes but no phenotype. A single method of analysis that jointly fits all genotypes in a Bayesian mixture model...

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Detalles Bibliográficos
Autores principales: MacLeod, I. M., Bowman, P. J., Vander Jagt, C. J., Haile-Mariam, M., Kemper, K. E., Chamberlain, A. J., Schrooten, C., Hayes, B. J., Goddard, M. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769584/
https://www.ncbi.nlm.nih.gov/pubmed/26920147
http://dx.doi.org/10.1186/s12864-016-2443-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769584/
https://www.ncbi.nlm.nih.gov/pubmed/26920147
http://dx.doi.org/10.1186/s12864-016-2443-6

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