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Exploiting biological priors and sequence variants enhances QTL discovery and genomic prediction of complex traits
BACKGROUND: Dense SNP genotypes are often combined with complex trait phenotypes to map causal variants, study genetic architecture and provide genomic predictions for individuals with genotypes but no phenotype. A single method of analysis that jointly fits all genotypes in a Bayesian mixture model...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769584/ https://www.ncbi.nlm.nih.gov/pubmed/26920147 http://dx.doi.org/10.1186/s12864-016-2443-6 |