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Epigenetic Studies Point to DNA Replication/Repair Genes as a Basis for the Heritable Nature of Long Term Complications in Diabetes

Metabolic memory (MM) is defined as the persistence of diabetic (DM) complications even after glycemic control is pharmacologically achieved. Using a zebrafish diabetic model that induces a MM state, we previously reported that, in this model, tissue dysfunction was of a heritable nature based on ce...

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Detalles Bibliográficos
Autores principales: Leontovich, Alexey A., Intine, Robert V., Sarras, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769771/
https://www.ncbi.nlm.nih.gov/pubmed/26981540
http://dx.doi.org/10.1155/2016/2860780