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Synthesis, In Vivo Anti-Inflammatory Activity, and Molecular Docking Studies of New Isatin Derivatives

A novel synthesis of 2-hydroxy-N′-(2-oxoindolin-3-ylidene) benzohydrazide derivatives was synthesized by the condensation of 2-hydroxybenzohydrazide with substituted isatins. The synthesized compounds were characterized by FT-IR, (1)H-NMR, and mass spectral data. Further, the compounds were screened...

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Detalles Bibliográficos
Autores principales: Jarapula, Ravi, Gangarapu, Kiran, Manda, Sarangapani, Rekulapally, Sriram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769772/
https://www.ncbi.nlm.nih.gov/pubmed/27022484
http://dx.doi.org/10.1155/2016/2181027