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Comparative mRNA Expression of eEF1A Isoforms and a PI3K/Akt/mTOR Pathway in a Cellular Model of Parkinson's Disease

The PI3K/Akt/mTOR pathway is one of dysregulated pathways in Parkinson's disease (PD). Previous studies in nonneuronal cells showed that Akt regulation can be increased by eukaryotic protein elongation factor 1 alpha 2 (eEF1A2). eEF1A2 is proposed to contribute protection against apoptotic deat...

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Detalles Bibliográficos
Autores principales: Khwanraj, Kawinthra, Madlah, Suriyat, Grataitong, Khwanthana, Dharmasaroja, Permphan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769776/
https://www.ncbi.nlm.nih.gov/pubmed/26981313
http://dx.doi.org/10.1155/2016/8716016